WB analysis of various sample lysates using GTX16389 Tyrosinase antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX16389 Tyrosinase antibody. Dilution : 1:1000 Loading : 25microg per lane
Tyrosinase antibody
GTX16389
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTYR
Overview
- SupplierGeneTex
- Product NameTyrosinase antibody
- Delivery Days Customer7
- Application Supplier NoteWB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7299
- Target nameTYR
- Target descriptiontyrosinase
- Target synonymsATN; CMM8; LB24-AB; monophenol monooxygenase; OCA1; OCA1A; OCAIA; oculocutaneous albinism IA; SHEP3; SK29-AB; tumor rejection antigen AB; tyrosinase
- HostRabbit
- IsotypeIgG
- Protein IDP14679
- Protein NameTyrosinase
- Scientific DescriptionThe enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3 half of this gene. [provided by RefSeq, Oct 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- A Novel and Effective Method for Human Primary Skin Melanocytes and Metastatic Melanoma Cell Isolation. Sciezynska A et al., 2021 Dec 13, Cancers (Basel)Read more
- The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated alpha-MSH in keratinocytes via Nrf2-mediated antioxidant pathways. Hseu YC et al., 2021 Aug, Redox BiolRead more
- Opsin 5 is a key regulator of ultraviolet radiation-induced melanogenesis in human epidermal melanocytes. Lan Y et al., 2021 Aug, Br J DermatolRead more