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WB analysis of various sample lysates using GTX16389 Tyrosinase antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX16389 Tyrosinase antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX16389 Tyrosinase antibody. Dilution : 1:1000 Loading : 25microg per lane

Tyrosinase antibody

GTX16389
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetTYR
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Overview

  • Supplier
    GeneTex
  • Product Name
    Tyrosinase antibody
  • Delivery Days Customer
    7
  • Application Supplier Note
    WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID7299
  • Target name
    TYR
  • Target description
    tyrosinase
  • Target synonyms
    ATN; CMM8; LB24-AB; monophenol monooxygenase; OCA1; OCA1A; OCAIA; oculocutaneous albinism IA; SHEP3; SK29-AB; tumor rejection antigen AB; tyrosinase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP14679
  • Protein Name
    Tyrosinase
  • Scientific Description
    The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3 half of this gene. [provided by RefSeq, Oct 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • A Novel and Effective Method for Human Primary Skin Melanocytes and Metastatic Melanoma Cell Isolation. Sciezynska A et al., 2021 Dec 13, Cancers (Basel)
    Read more
  • The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated alpha-MSH in keratinocytes via Nrf2-mediated antioxidant pathways. Hseu YC et al., 2021 Aug, Redox Biol
    Read more
  • Opsin 5 is a key regulator of ultraviolet radiation-induced melanogenesis in human epidermal melanocytes. Lan Y et al., 2021 Aug, Br J Dermatol
    Read more

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Lane 1: Mouse Eye lysates; Lane 2: Mouse Skin lysates probed with Tyrosinase Polyclonal Antibody, Unconjugated (bs-0819R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
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