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UAP1 antibody [N1C3]

GTX103592
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetUAP1
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Overview

  • Supplier
    GeneTex
  • Product Name
    UAP1 antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6675
  • Target name
    UAP1
  • Target description
    UDP-N-acetylglucosamine pyrophosphorylase 1
  • Target synonyms
    AGX, AGX1, AGX2, SPAG2, UDP-N-acetylhexosamine pyrophosphorylase, UDP-N-acetylgalactosamine pyrophosphorylase, UDP-N-acetylglucosamine diphosphorylase 1, UDP-N-acetylhexosamine pyrophosphorylase 1, antigen X, protein-pyrophosphorylation enzyme, sperm associated antigen 2, testis tissue sperm-binding protein Li 37a
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ16222
  • Protein Name
    UDP-N-acetylhexosamine pyrophosphorylase
  • Scientific Description
    Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Andres LM, Blong IW, Evans AC, et al. Chemical Modulation of Protein O-GlcNAcylation via OGT Inhibition Promotes Human Neural Cell Differentiation. ACS Chem Biol. 2017,12(8):2030-2039. doi: 10.1021/acschembio.7b00232
    Read this paper
  • Yu SH, Boyce M, Wands AM, et al. Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners. Proc Natl Acad Sci U S A. 2012,109(13):4834-9. doi: 10.1073/pnas.1114356109
    Read this paper