
Western Blot All lanes: UBR2 antibody at 3microg/ml + Mouse liver tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 201, 50, 67 kDa Observed band size: 201 kDa
UBR2 Antibody
CSB-PA809001LA01HU
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetUBR2
Overview
- SupplierCusabio
- Product NameUBR2 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23304
- Target nameUBR2
- Target descriptionubiquitin protein ligase E3 component n-recognin 2
- Target synonymsC6orf133, bA49A4.1, dJ242G1.1, dJ392M17.3, E3 ubiquitin-protein ligase UBR2, RING-type E3 ubiquitin transferase UBR2, ubiquitin-protein ligase E3-alpha-2, ubiquitin-protein ligase E3-alpha-II
- HostRabbit
- IsotypeIgG
- Protein IDQ8IWV8
- Protein NameE3 ubiquitin-protein ligase UBR2
- Scientific DescriptionE3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161






