UC-514321 [299420-83-0]

MedChem Express

UC-514321 [299420-83-0]

5

299420-83-0

Research Use Only

98.0

C26H35NO5

441.56

UC-514321, a structural analog of NSC370284 with higher activity, directly targets STAT3/5 and represses TET1 expression, but not TET2 or TET3. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity[1].

OC1=C(C=C2OCOC2=C1)C(N3CCOCC3)C4=CC(C(C)(C)C)=C(C(C(C)(C)C)=C4)O

-20°C,2°C to 8°C

12352200