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UC-514321 [299420-83-0]

UC-514321 [299420-83-0]

T13950
TargetMol Chemicals
CAS Number299420-83-0
Product group Chemicals
Estimated Purity97%
Molecular Weight441.56
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    UC-514321 [299420-83-0]
  • Delivery Days Customer
    4
  • CAS Number
    299420-83-0
  • Certification
    Research Use Only
  • Chemical Name
    UC-514321
  • Estimated Purity
    97%
  • Molecular Formula
    C26H35NO5
  • Molecular Weight
    441.56
  • Scientific Description
    UC-514321 directly targets STAT3/5 and represses TET1 expression. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity.
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(N1CCOCC1)c1cc2OCOc2cc1O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Jiang X, Hu C, Ferchen K, et al. Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia. Nat Commun. 2017,8(1):2099. doi: 10.1038/s41467-017-02290-w
    Read this paper

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