Western Blot Positive WB detected in: SH-SY5Y whole cell lysate, LO2 whole cell lysate, 293T whole cell lysate, HL-60 whole cell lysate All lanes: UGT1A1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 60, 50 kDa Observed band size: 60 kDa
UGT1A1 Antibody
CSB-PA025570LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetUGT1A1
Overview
- SupplierCusabio
- Product NameUGT1A1 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID54658
- Target nameUGT1A1
- Target descriptionUDP glucuronosyltransferase family 1 member A1
- Target synonymsBILIQTL1; bilirubin UDP-glucuronosyltranserase; bilirubin UDP-glucuronosyltransferase 1-1; bilirubin UDP-glucuronosyltransferase isozyme 1; bilirubin-specific UDPGT isozyme 1; GNT1; HUG-BR1; UDP glucuronosyltransferase 1 family, polypeptide A1; UDP glycosyltransferase 1 family, polypeptide A1; UDP-glucuronosyltransferase 1A; UDP-glucuronosyltransferase 1-A; UDP-glucuronosyltransferase 1A1; UDPGT; UDPGT 1-1; UGT1; UGT1*1; UGT1.1; UGT1-01; UGT1A; UGT-1A
- HostRabbit
- IsotypeIgG
- Protein IDP22309
- Protein NameUDP-glucuronosyltransferase 1-1
- Scientific DescriptionUDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203