UVSSA antibody [GT816]

GeneTex

UVSSA antibody [GT816]

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

GT816

1 mg/ml

Unconjugated

UVSSA

UV stimulated scaffold protein A

KIAA1530; UVSS3; UV-stimulated scaffold protein A

Mouse

IgG1

UV-stimulated scaffold protein A

The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in this gene can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Human

-20°C or -80°C,2°C to 8°C

12352203