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UVSSA antibody [N1N2], N-term

GTX106751
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetUVSSA
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Overview

  • Supplier
    GeneTex
  • Product Name
    UVSSA antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID57654
  • Target name
    UVSSA
  • Target description
    UV stimulated scaffold protein A
  • Target synonyms
    KIAA1530; UVSS3; UV-stimulated scaffold protein A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ2YD98
  • Protein Name
    UV-stimulated scaffold protein A
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Transcription-Coupled Repair of DNA Interstrand Crosslinks by UVSSA.
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  • The UVSSA protein is part of a genome integrity homeostasis network with links to transcription-coupled DNA repair and ATM signaling. Kordon MM et al., 2022 Mar 15, Proc Natl Acad Sci U S A
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  • The UVSSA complex alleviates MYC-driven transcription stress. Sato M et al., 2021 Feb 1, J Cell Biol
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  • Inhibition of UVSSA ubiquitination suppresses transcription-coupled nucleotide excision repair deficiency caused by dissociation from USP7. Higa M et al., 2018 Mar, FEBS J
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  • Stabilization of Ultraviolet (UV)-stimulated Scaffold Protein A by Interaction with Ubiquitin-specific Peptidase 7 Is Essential for Transcription-coupled Nucleotide Excision Repair. Higa M et al., 2016 Jun 24, J Biol Chem
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  • Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair. Zhang X et al., 2012 May, Nat Genet
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