VAV1 antibody [GT557] detects VAV1 protein by Western blot analysis. A. 30 μg Jurkat whole cell lysate/extract B. 30 μg NCI-H929 whole cell lysate/extract 7.5 % SDS-PAGE VAV1 antibody [GT557] (GTX629749) dilution: 1:1000
![VAV1 antibody [GT557] detects VAV1 protein at cell membrane and cytoplasm by immunofluorescent analysis. Sample: Jurkat cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: VAV1 stained by VAV1 antibody [GT557] (GTX629749) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920). Scale bar= 10 μm.](https://www.genetex.com/upload/website/prouct_img/normal/GTX629749/GTX629749_41428_20190123_ICC_IF_w_23061202_715.webp "VAV1 antibody [GT557] detects VAV1 protein at cell membrane and cytoplasm by immunofluorescent analysis. Sample: Jurkat cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: VAV1 stained by VAV1 antibody [GT557] (GTX629749) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920). Scale bar= 10 μm.")
![VAV1 antibody [GT557] detects VAV1 protein by immunohistochemical analysis. Sample: Paraffin-embedded mouse spleen. VAV1 stained by VAV1 antibody [GT557] (GTX629749) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX629749/GTX629749_41428_20180525_IHC-P_M_w_23061202_273.webp "VAV1 antibody [GT557] detects VAV1 protein by immunohistochemical analysis. Sample: Paraffin-embedded mouse spleen. VAV1 stained by VAV1 antibody [GT557] (GTX629749) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min")
VAV1 antibody [GT557] detects VAV1 protein by Western blot analysis. A. 30 μg Jurkat whole cell lysate/extract B. 30 μg NCI-H929 whole cell lysate/extract 7.5 % SDS-PAGE VAV1 antibody [GT557] (GTX629749) dilution: 1:1000
VAV1 antibody [GT557]
GTX629749
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetVAV1
Overview
- SupplierGeneTex
- Product NameVAV1 antibody [GT557]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT557
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7409
- Target nameVAV1
- Target descriptionvav guanine nucleotide exchange factor 1
- Target synonymsVAV, proto-oncogene vav, vav 1 guanine nucleotide exchange factor, vav 1 oncogene
- HostMouse
- IsotypeIgG2b
- Protein IDP15498
- Protein NameProto-oncogene vav
- Scientific DescriptionThe protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
Datasheet
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