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VAV1 antibody

GTX103489
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetVAV1
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Overview

  • Supplier
    GeneTex
  • Product Name
    VAV1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.49 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7409
  • Target name
    VAV1
  • Target description
    vav guanine nucleotide exchange factor 1
  • Target synonyms
    proto-oncogene vav; VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP15498
  • Protein Name
    Proto-oncogene vav
  • Scientific Description
    The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • A Fucoxanthinol Induces Apoptosis in a Pancreatic Intraepithelial Neoplasia Cell. Terasaki M et al., 2021 Mar-Apr, Cancer Genomics Proteomics
    Read more
  • CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration. Chiang YJ et al., 2013, PLoS One
    Read more

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