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IP analysis of K562 cell extracts using GTX24763 VAV1 (phospho Tyr160) antibody. The primary antibody was prior incubate with no peptide (1), the non-phosphopeptide corresponding to the immunogen (2), a generic phosphotyrosine containing peptide (3), or, the phosphopeptide immunogen (4) WB antibody dilution : 0.5 microg/ml
IP analysis of K562 cell extracts using GTX24763 VAV1 (phospho Tyr160) antibody. The primary antibody was prior incubate with no peptide (1), the non-phosphopeptide corresponding to the immunogen (2), a generic phosphotyrosine containing peptide (3), or, the phosphopeptide immunogen (4) WB antibody dilution : 0.5 microg/ml
IP analysis of K562 cell extracts using GTX24763 VAV1 (phospho Tyr160) antibody. The primary antibody was prior incubate with no peptide (1), the non-phosphopeptide corresponding to the immunogen (2), a generic phosphotyrosine containing peptide (3), or, the phosphopeptide immunogen (4) WB antibody dilution : 0.5 microg/ml

VAV1 (phospho Tyr160) antibody

GTX24763
GeneTex
ApplicationsImmunoPrecipitation, Western Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetVAV1
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Overview

  • Supplier
    GeneTex
  • Product Name
    VAV1 (phospho Tyr160) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 0.1-1 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID7409
  • Target name
    VAV1
  • Target description
    vav guanine nucleotide exchange factor 1
  • Target synonyms
    proto-oncogene vav; VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP15498
  • Protein Name
    Proto-oncogene vav
  • Scientific Description
    This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203