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WB (peptide competition) analysis of Cos7 cells over-expressing murine Vav3 were serum starved and left treated (Lane 1) or treated (Lane 2-5) with EGF using GTX24764 VAV3 (phospho Tyr173) antibody prior incubated with the non-phospho immunogen (Lane 3), a generic (pY) peptide (Lane 4), or, the phosphopeptide immunogen (Lane 5) control. The data show that only the immunogen phosphopeptide blocks the signal, demonstrating the specificity of the antibody.
WB (peptide competition) analysis of Cos7 cells over-expressing murine Vav3 were serum starved and left treated (Lane 1) or treated (Lane 2-5) with EGF using GTX24764 VAV3 (phospho Tyr173) antibody prior incubated with the non-phospho immunogen (Lane 3), a generic (pY) peptide (Lane 4), or, the phosphopeptide immunogen (Lane 5) control. The data show that only the immunogen phosphopeptide blocks the signal, demonstrating the specificity of the antibody.
WB (peptide competition) analysis of Cos7 cells over-expressing murine Vav3 were serum starved and left treated (Lane 1) or treated (Lane 2-5) with EGF using GTX24764 VAV3 (phospho Tyr173) antibody prior incubated with the non-phospho immunogen (Lane 3), a generic (pY) peptide (Lane 4), or, the phosphopeptide immunogen (Lane 5) control. The data show that only the immunogen phosphopeptide blocks the signal, demonstrating the specificity of the antibody.

VAV3 (phospho Tyr173) antibody - Orthogonal Validated

Research Use Only
GTX24764
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetVAV3
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    VAV3 (phospho Tyr173) antibody - Orthogonal Validated
  • Delivery Days Customer
    9
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID10451
  • Target name
    VAV3
  • Target description
    vav guanine nucleotide exchange factor 3
  • Target synonyms
    guanine nucleotide exchange factor VAV3; vav 3 guanine nucleotide exchange factor; vav 3 oncogene; VAV-3
  • Host
    Rabbit
  • Isotype
    IgG
  • Modification Type
    Phosphorylated
  • Scientific Description
    This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203