VCAM1 / CD106 antibody [M/K-2]

GeneTex

VCAM1 / CD106 antibody [M/K-2]

9

Present on the +/+ 2.4 stromal cell clone, large cells in bone marrow, and a subset of thymic macrophages. The stromal cell antigen is also detectable on the EOMA and BMS2 endothelial cell lines. Reacts with all known isoforms of murine VCAM-1. Murine vas

IF: Use at an assay dependent dilution. IHC-Fr: (Not suitable for use with parafin sections) Use at an assay dependent dilution. FuncS: Use at an assay dependent dilution. Studies of cell-cell interaction. Cell adhesion assays. Inhibition of lymphopoiesis in Whitlock-Witte long term marrow cultures. Immunoprecipitation of the VCAM1 integrin complex. Optimal dilutions/concentrations should be determined by the end user.

ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

M/K-2

0.5 mg/ml

Unconjugated

Liquid

VCAM1

vascular cell adhesion molecule 1

CD106; CD106 antigen; INCAM-100; vascular cell adhesion protein 1

Rat

IgG1

Vascular cell adhesion protein 1

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]

Mouse

-20°C or -80°C,2°C to 8°C

12352203