Bio-Connect

VDR agonist 1 [2269494-43-9]

HY-114310
MedChem Express
CAS Number2269494-43-9
Product group Chemicals
Molecular Weight509.77
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Overview

  • Supplier
    MedChem Express
  • Product Name
    VDR agonist 1 [2269494-43-9]
  • Delivery Days Customer
    10
  • CAS Number
    2269494-43-9
  • Certification
    Research Use Only
  • Molecular Formula
    C32H51N3O2
  • Molecular Weight
    509.77
  • Scientific Description
    VDR agonist 1 (compound 28) is a nonsteroidal Vitamin D receptor (VDR) agonist, with an IC50 of 690 nM in MCF-7 cells. VDR agonist 1 arrests the cell cycle through the up-regulation of p21 and p27, promotes apoptosis by increasing the expression of BAX and decrease the expression of Bcl-2[1].
  • SMILES
    O=C(C1=CC(C(CC)(C2=CC=C(/C=C/C(O)(CC)CC)C(C)=C2)CC)=CN1CC)NCCN(CC)CC
  • UNSPSC
    12352200