VDR agonist 1 [2269494-43-9]
HY-114310
CAS Number2269494-43-9
Product group Chemicals
Molecular Weight509.77
Overview
- SupplierMedChem Express
- Product NameVDR agonist 1 [2269494-43-9]
- Delivery Days Customer10
- CAS Number2269494-43-9
- CertificationResearch Use Only
- Molecular FormulaC32H51N3O2
- Molecular Weight509.77
- Scientific DescriptionVDR agonist 1 (compound 28) is a nonsteroidal Vitamin D receptor (VDR) agonist, with an IC50 of 690 nM in MCF-7 cells. VDR agonist 1 arrests the cell cycle through the up-regulation of p21 and p27, promotes apoptosis by increasing the expression of BAX and decrease the expression of Bcl-2[1].
- SMILESO=C(C1=CC(C(CC)(C2=CC=C(/C=C/C(O)(CC)CC)C(C)=C2)CC)=CN1CC)NCCN(CC)CC
- UNSPSC12352200
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