VDR agonist 1 [2269494-43-9]

TargetMol Chemicals

VDR agonist 1

114

2269494-43-9

Chemical

Research Use Only

VDR agonist 1

C32H51N3O2

509.77

VDR agonist 1 (compound 28), a nonsteroidal Vitamin D receptor (VDR) agonist, demonstrates potent activity with a low IC 50 of 690 nM in MCF-7 cells. It inhibits cell cycle progression through upregulation of p21 and p27, and induces apoptosis by elevating BAX expression while reducing Bcl-2 levels [1].

3 years

C(CC)(CC)(C=1C=C(C(NCCN(CC)CC)=O)N(CC)C1)C2=CC(C)=C(/C=C/C(CC)(CC)O)C=C2

-20°C

12352200