Western blot analysis of extracts of various cell lines using VDR Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using VDR Polyclonal Antibody at 1:1000 dilution.
VDR Polyclonal Antibody
E-AB-60676
Product group Antibodies
Overview
- SupplierElabscience
- Product NameVDR Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.
- UNSPSC12352203