Vemurafenib

MedChem Express

Vemurafenib [918504-65-1]

10

918504-65-1

Research Use Only

99.85

C23H18ClF2N3O3S

489.92

Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC 50 s of 31 and 48 nM for RAF V600E and c-RAF-1, respectively [1] [4] . Vemurafenib induces cell autophagy [5] .

FC1=CC=C(C(F)=C1C(C2=CNC3=NC=C(C=C32)C4=CC=C(C=C4)Cl)=O)NS(CCC)(=O)=O

-20°C,2°C to 8°C

12352200