Vemurafenib (PLX4032)
M1761
CAS Number918504-65-1
Product group Chemicals
Estimated Purity0.9934
Molecular Weight489.92
Overview
- SupplierAbMole BioScience
- Product NameVemurafenib (PLX4032)
- Delivery Days Customer9
- CAS Number918504-65-1
- Category SupplierChemical
- Estimated Purity0.9934
- Molecular FormulaC23H18ClF2N3O3S
- Molecular Weight489.92
- Scientific DescriptionVemurafenib (PLX4032) is a first-in-class, potent, selective inhibitor of B-Raf that inhibits RAFV600E and C-RAF-1 activity with IC50s of 31 nM and 48 nM, respectively.In addition, Vemurafenib induces autophagy.
- SMILESCCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(C=C23)C4=CC=C(Cl)C=C4
- UNSPSC12352200