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Vemurafenib (PLX4032)

M1761
AbMole BioScience
CAS Number918504-65-1
DownloadDatasheet
Product group Chemicals
Estimated Purity0.9934
Molecular Weight489.92
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Vemurafenib (PLX4032)
  • Delivery Days Customer
    9
  • CAS Number
    918504-65-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.9934
  • Molecular Formula
    C23H18ClF2N3O3S
  • Molecular Weight
    489.92
  • Scientific Description
    Vemurafenib (PLX4032) is a first-in-class, potent, selective inhibitor of B-Raf that inhibits RAFV600E and C-RAF-1 activity with IC50s of 31 nM and 48 nM, respectively.In addition, Vemurafenib induces autophagy.
  • SMILES
    CCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(C=C23)C4=CC=C(Cl)C=C4
  • UNSPSC
    12352200

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