Venetoclax (ABT-199) [1257044-40-8]

Selleck Chemicals

Venetoclax (ABT-199) [1257044-40-8]

9

Research Use Only

Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of 4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1. Venetoclax is reported to induce cell growth suppression, apoptosis, cell cycle arrest, and autophagy in triple negative breast cancer MDA-MB-231 cells. Phase 3.

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