Vimentin antibody

GeneTex

Vimentin antibody [J144]

9

Detects the intermediate filament protein vimentin. The antibody gives a positive reaction with connective tissue, endothelial cells, vascular smooth muscle cells and astrocytes.

IHC and WB: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.

Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

1 mg/ml

Unconjugated

Liquid

VIM

vimentin

epididymis secretory sperm binding protein; vimentin

Mouse

IgM

Vimentin

This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]

Human

-20°C or -80°C,2°C to 8°C

12352203