Voruciclib [1000023-04-0]

TargetMol Chemicals

Voruciclib [1000023-04-0]

9

1000023-04-0

Chemical

Research Use Only

Voruciclib

C22H19ClF3NO5

469.84

Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM) that represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma and effectively blocks CDK9, the transcriptional regulator of MCL-1.

3 years

CN1CC[C@H]([C@@H]1CO)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1Cl)C(F)(F)F

-20°C

12352200