VU-29

Biorbyt

VU-29 [890764-36-0]

10

890764-36-0

Research Use Only

C22H16N4O3

384.3874445

VU-29 (DPAP) is a potent, selective and allosteric potentiator of rat mGlu5 receptor with EC50 of 9 nM, displays > 50-fold selectivity over mGlu1 and mGlu2 receptor (EC50=557 nM and 1.51 uM).

C1(N2C(NC(=O)C3C=CC([N+]([O-])=O)=CC=3)=CC(C3C=CC=CC=3)=N2)C=CC=CC=1

12352200