VU0361737

MedChem Express

VU0361737 [1161205-04-4]

10

1161205-04-4

Research Use Only

99.79

C13H11ClN2O2

262.69

VU0361737 (ML-128) is a potent, selective and CNS penetrant positive allosteric modulator of metabotropic glutamate receptor 4 ( mGluR 4 PAM ), with EC 50 s of 240 nM and 110 nM for human and rat mGluR 4 receptors, respectively. VU0361737 has neuroprotective effect. VU0361737 is potential for Parkinsons disease research [1] [2] .

ClC(C=C1)=C(OC)C=C1NC(C2=NC=CC=C2)=O

-20°C,2°C to 8°C

12352200