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VU0361737 [1161205-04-4]

VU0361737 [1161205-04-4]

T6726
TargetMol Chemicals
CAS Number1161205-04-4
Product group Chemicals
Estimated Purity99.86%
Molecular Weight262.69
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    VU0361737 [1161205-04-4]
  • Delivery Days Customer
    9
  • CAS Number
    1161205-04-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    VU0361737
  • Estimated Purity
    99.86%
  • Molecular Formula
    C13H11ClN2O2
  • Molecular Weight
    262.69
  • Scientific Description
    VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of the mGlu4 receptor with an EC50 of 240 nM for human receptors and 110 nM for rat receptors. It exhibits weak activity at mGlu5 and mGlu8 receptors and is inactive at mGlu1, mGlu2, mGlu3, mGlu6, and mGlu7 receptors. The compound can penetrate the CNS.
  • Shelf life instruction
    3 years
  • SMILES
    COc1cc(NC(=O)c2ccccn2)ccc1Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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