VU0361737 [1161205-04-4]
T6726
CAS Number1161205-04-4
Product group Chemicals
Estimated Purity99.86%
Molecular Weight262.69
Overview
- SupplierTargetMol Chemicals
- Product NameVU0361737 [1161205-04-4]
- Delivery Days Customer9
- CAS Number1161205-04-4
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameVU0361737
- Estimated Purity99.86%
- Molecular FormulaC13H11ClN2O2
- Molecular Weight262.69
- Scientific DescriptionVU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of the mGlu4 receptor with an EC50 of 240 nM for human receptors and 110 nM for rat receptors. It exhibits weak activity at mGlu5 and mGlu8 receptors and is inactive at mGlu1, mGlu2, mGlu3, mGlu6, and mGlu7 receptors. The compound can penetrate the CNS.
- Shelf life instruction3 years
- SMILESCOc1cc(NC(=O)c2ccccn2)ccc1Cl
- Storage Instruction-20°C
- UNSPSC12352200