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VZ185 [2306193-61-1]

Research Use Only
HY-114322
MedChem Express
CAS Number2306193-61-1
Product group Chemicals
Estimated Purity97%
Molecular Weight995.21
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    VZ185 [2306193-61-1]
  • Delivery Days Customer
    10
  • CAS Number
    2306193-61-1
  • Certification
    Research Use Only
  • Estimated Purity
    97%
  • Molecular Formula
    C53H67FN8O8S
  • Molecular Weight
    995.21
  • Scientific Description
    VZ185 is a potent, fast, and selective von Hippel-Lindau based dual degrader probe of BRD9 and BRD7 with DC50s of 4.5 and 1.8 nM, respectively. VZ185 is cytotoxic in EOL-1 and A-402 cells, with EC50s of 3 nM and 40 nM, respectively.
  • SMILES
    O=C([C@H]1N(C([C@@H](NC(C2(F)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3OCCCCCN5CCN(CC6=C(OC)C=C(C(C7=CC=NC=C87)=CN(C)C8=O)C=C6OC)CC5
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352200