WAC Antibody, FITC conjugated
CSB-PA861133HC01HU
ReactivityHuman
Product group Antibodies
TargetWAC
Overview
- SupplierCusabio
- Product NameWAC Antibody, FITC conjugated
- Delivery Days Customer20
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateFITC
- Gene ID51322
- Target nameWAC
- Target descriptionWW domain containing adaptor with coiled-coil
- Target synonymsBM-016; DESSH; PRO1741; WW domain-containing adapter protein with coiled-coil; Wwp4
- HostRabbit
- IsotypeIgG
- Protein IDQ9BTA9
- Protein NameWW domain-containing adapter protein with coiled-coil
- Scientific DescriptionActs as a linker between gene transcription and histone H2B monoubiquitination at Lys-120 (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203