WDYHV1 Antibody

Cusabio

WDYHV1 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

NTAQ1

N-terminal glutamine amidase 1

C8orf32, WDYHV1, protein N-terminal glutamine amidohydrolase, N-terminal Gln amidase, WDYHV motif containing 1, WDYHV motif-containing protein 1, nt(Q)-amidase, protein NH2-terminal glutamine deamidase

Rabbit

IgG

Protein N-terminal glutamine amidohydrolase

Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine (By similarity).

Human, Mouse

-20°C or -80°C

41116161