WDYHV1 antibody

GeneTex

WDYHV1 antibody

9

ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.58 mg/ml

Unconjugated

NTAQ1

N-terminal glutamine amidase 1

C8orf32; nt(Q)-amidase; N-terminal Gln amidase; protein NH2-terminal glutamine deamidase; protein N-terminal glutamine amidohydrolase; WDYHV motif containing 1; WDYHV motif-containing protein 1; WDYHV1

Rabbit

IgG

Protein N-terminal glutamine amidohydrolase

Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203