Wedelolactone

MedChem Express

Wedelolactone [524-12-9]

5

524-12-9

Research Use Only

99.91

C16H10O7

314.25

Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibits the IKK Complex. Wedelolactone also inhibits 5-lipoxygenase ( 5-Lox ) with an IC 50 of 2.5 microM. Wedelolactone induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCepsilon without inhibiting Akt. Wedelolactone can extract from Eclipta alba, and it can be used for the research of cancer [1] [2] [3] .

O=C1C2=C(OC3=CC(O)=C(O)C=C32)C4=C(O)C=C(OC)C=C4O1

-20°C

12352200