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IHC-P analysis of human breast using GTX89319 WNT3 antibody, Internal. Antigen retrieval : citrate buffer pH 6 Dilution : 2microg/ml
IHC-P analysis of human breast using GTX89319 WNT3 antibody, Internal. Antigen retrieval : citrate buffer pH 6 Dilution : 2microg/ml
IHC-P analysis of human breast using GTX89319 WNT3 antibody, Internal. Antigen retrieval : citrate buffer pH 6 Dilution : 2microg/ml

Wnt3 antibody, Internal

GTX89319
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetWNT3
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Overview

  • Supplier
    GeneTex
  • Product Name
    Wnt3 antibody, Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1-3microg/ml. IHC-P: 2-4microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.50 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7473
  • Target name
    WNT3
  • Target description
    Wnt family member 3
  • Target synonyms
    INT4; proto-oncogene Int-4 homolog; proto-oncogene Wnt-3; TETAMS; wingless-type MMTV integration site family, member 3; WNT-3 proto-oncogene protein
  • Host
    Goat
  • Isotype
    IgG
  • Protein IDP56703
  • Protein Name
    Proto-oncogene Wnt-3
  • Scientific Description
    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Identification of candidate lncRNAs and circRNAs regulating WNT3/beta-catenin signaling in essential hypertension. Yin L et al., 2020 May 11, Aging (Albany NY)
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