WZ-3146

MedChem Express

WZ-3146 [1214265-56-1]

10

1214265-56-1

Research Use Only

99.63

C24H25ClN6O2

464.95

WZ3146 is a mutant selective EGFR inhibitor with IC50s of 2, 2, 5, 14 and 66 nM for EGFRL858R, EGFRL858R/T790M, EGFRE746_A750, EGFRE746_A750/T790M and EGFR, respectively.

CN1CCN(C2=CC=C(C=C2)NC3=NC=C(C(OC4=CC(NC(C=C)=O)=CC=C4)=N3)Cl)CC1

-20°C,2°C to 8°C

12352200