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WZ3146

M5346
AbMole BioScience
CAS Number1214265-56-1
DownloadDatasheet
Product group Chemicals
Estimated Purity>99.0%
Molecular Weight464.95
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    WZ3146
  • Delivery Days Customer
    9
  • CAS Number
    1214265-56-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >99.0%
  • Molecular Formula
    C24H25ClN6O2
  • Molecular Weight
    464.95
  • Scientific Description
    WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).
  • SMILES
    CN1CCN(CC1)C2=CC=C(NC3=NC=C(Cl)C(=N3)OC4=CC(=CC=C4)NC(=O)C=C)C=C2
  • UNSPSC
    12352200