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ProductsBack/XRCC1 antibody [33-2-5]
IHC-P analysis of human testis tissue using GTX21838 XRCC1 antibody [33-2-5].
IHC-P analysis of human testis tissue using GTX21838 XRCC1 antibody [33-2-5].
IHC-P analysis of human testis tissue using GTX21838 XRCC1 antibody [33-2-5].

XRCC1 antibody [33-2-5]

GTX21838
GeneTex
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetXRCC1
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Overview

  • Supplier
    GeneTex
  • Product Name
    XRCC1 antibody [33-2-5]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    33-2-5
  • Conjugate
    Unconjugated
  • Gene ID7515
  • Target name
    XRCC1
  • Target description
    X-ray repair cross complementing 1
  • Target synonyms
    DNA repair protein XRCC1; RCC; SCAR26; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross-complementing protein 1
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP18887
  • Protein Name
    DNA repair protein XRCC1
  • Scientific Description
    The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • WRN regulates pathway choice between classical and alternative non-homologous end joining. Shamanna RA et al., 2016 Dec 6, Nat Commun
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  • Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1. Kong X et al., 2011, PLoS One
    Read more
  • Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells. Kong X et al., 2009 May, Nucleic Acids Res
    Read more