XRCC1 antibody [33-2-5]

Name: XRCC1 antibody [33-2-5]
SKU: GTX21838_G10
Availability: BackOrder

GTX21838

ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetXRCC1

Overview

Supplier
GeneTex
Product Name
XRCC1 antibody [33-2-5]
Delivery Days Customer
9
Application Supplier Note
IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
33-2-5
Conjugate
Unconjugated
Gene ID7515
Target name
XRCC1
Target description
X-ray repair cross complementing 1
Target synonyms
RCC, SCAR26, DNA repair protein XRCC1, X-ray repair complementing defective repair in Chinese hamster cells 1, X-ray repair cross-complementing protein 1
Host
Mouse
Isotype
IgG2b
Protein IDP18887
Protein Name
DNA repair protein XRCC1
Scientific Description
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Storage Instruction
2°C to 8°C
UNSPSC
12352203

Shamanna RA, Lu H, de Freitas JK, et al. WRN regulates pathway choice between classical and alternative non-homologous end joining. Nat Commun. 2016,7:13785. doi: 10.1038/ncomms13785
Read this paper
Kong X, Stephens J, Ball AR Jr, et al. Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1. PLoS One. 2011,6(8):e23548. doi: 10.1371/journal.pone.0023548
Read this paper
Kong X, Mohanty SK, Stephens J, et al. Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells. Nucleic Acids Res. 2009,37(9):e68. doi: 10.1093/nar/gkp221
Read this paper