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ProductsBack/Y134 [849662-80-2]

Y134 [849662-80-2]

Research Use Only
HY-103457
MedChem Express
CAS Number849662-80-2
DownloadMSDS
Product group Chemicals
Estimated Purity98.34
Molecular Weight472.60
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Y134 [849662-80-2]
  • Delivery Days Customer
    5
  • CAS Number
    849662-80-2
  • Certification
    Research Use Only
  • Estimated Purity
    98.34
  • Molecular Formula
    C28H28N2O3S
  • Molecular Weight
    472.60
  • Scientific Description
    Y134 is a selective and orally active oestrogen receptor (ER) modulator (SERM), exhibits potent antagonist activity at ERalpha and ERbeta. Y134 shows 121.1-fold selectivity for ERalpha (Ki=0.09 nM) over ERbeta (Ki=11.31 nM). Y134 inhibits oestrogen-stimulated proliferation of ER-positive human breast cancer cells[1].
  • SMILES
    O=C(C1=C(C2=CC=C(O)C=C2)SC3=CC(O)=CC=C31)C4=CC=C(N5CCN(C(C)C)CC5)C=C4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200