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WB analysis of U-251 MG cell lysate using GTX81909 YB1 antibody, C-term. Loading : 35ug Dilution : 1:1000
WB analysis of U-251 MG cell lysate using GTX81909 YB1 antibody, C-term. Loading : 35ug Dilution : 1:1000
WB analysis of U-251 MG cell lysate using GTX81909 YB1 antibody, C-term. Loading : 35ug Dilution : 1:1000

YB1 antibody, C-term

GTX81909
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetYBX1
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Overview

  • Supplier
    GeneTex
  • Product Name
    YB1 antibody, C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. ICC/IF: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID4904
  • Target name
    YBX1
  • Target description
    Y-box binding protein 1
  • Target synonyms
    BP-8; CBF-A; CCAAT-binding transcription factor I subunit A; CSDA2; CSDB; DBPB; DNA-binding protein B; EFI-A; enhancer factor I subunit A; major histocompatibility complex, class II, Y box-binding protein I; MDR-NF1; NSEP1; NSEP-1; nuclease-sensitive element-binding protein 1; YB1; YB-1; Y-box transcription factor; Y-box-binding protein 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP67809
  • Protein Name
    Nuclease-sensitive element-binding protein 1
  • Scientific Description
    This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1-mucin pathway. Lv J et al., 2022 Mar, Nat Cell Biol
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