YKL-05-099

MedChem Express

YKL-05-099 [1936529-65-5]

10

1936529-65-5

Research Use Only

99.76

C32H34ClN7O3

600.11

YKL-05-099 is a salt-inducible kinase ( SIK ) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC 50 s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC 50 =40 nM) [1] .

O=C1N(C2=NC=C(OC)C=C2)C3=NC(NC4=CC=C(C5CCN(C)CC5)C=C4OC)=NC=C3CN1C6=C(C)C=CC=C6Cl

-20°C,2°C to 8°C

12352200