YKL-5-124 [1957203-01-8]

TargetMol Chemicals

YKL-5-124 [1957203-01-8]

9

1957203-01-8

Chemical

Research Use Only

YKL-5-124

99.50%

C28H33N7O3

515.61

YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays biochemical and cellular selectivity for CDK7 over CDK12/13.

3 years

CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2C1(C)C)c1ccccc1

-20°C

12352200