YUM70

MedChem Express

YUM70 [423145-35-1]

10

423145-35-1

Research Use Only

98.01

C21H19ClN2O4

398.84

YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78) , with an IC 50 of 1.5 microM for inhibiting GRP78 ATPase activity of the full-length protein. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer. YUM70 also has in vivo efficacy in a pancreatic cancer xenograft model [1] .

CCCC(NC(C1=CC=C(OCO2)C2=C1)C3=CC(Cl)=C4C=CC=NC4=C3O)=O

-20°C,2°C to 8°C

12352200