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YUM70 [423145-35-1]

YUM70 [423145-35-1]

T8901
TargetMol Chemicals
CAS Number423145-35-1
Product group Chemicals
Estimated Purity98.01%
Molecular Weight398.84
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    YUM70 [423145-35-1]
  • Delivery Days Customer
    4
  • CAS Number
    423145-35-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    YUM70
  • Estimated Purity
    98.01%
  • Molecular Formula
    C21H19ClN2O4
  • Molecular Weight
    398.84
  • Scientific Description
    YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 microM for inhibiting GRP78 ATPase activity of the full-length protein. It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.
  • Shelf life instruction
    3 years
  • SMILES
    CCCC(=O)NC(c1ccc2OCOc2c1)c1cc(Cl)c2cccnc2c1O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer. Samanta S et al., 2021 Apr 1, Cancer Res
    Read more

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