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YUM70 [423145-35-1]
T8901
CAS Number423145-35-1
Product group Chemicals
Estimated Purity98.01%
Molecular Weight398.84
Overview
- SupplierTargetMol Chemicals
- Product NameYUM70 [423145-35-1]
- Delivery Days Customer4
- CAS Number423145-35-1
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameYUM70
- Estimated Purity98.01%
- Molecular FormulaC21H19ClN2O4
- Molecular Weight398.84
- Scientific DescriptionYUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 microM for inhibiting GRP78 ATPase activity of the full-length protein. It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.
- Shelf life instruction3 years
- SMILESCCCC(=O)NC(c1ccc2OCOc2c1)c1cc(Cl)c2cccnc2c1O
- Storage Instruction-20°C
- UNSPSC12352200
References
- The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer. Samanta S et al., 2021 Apr 1, Cancer ResRead more