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Chemical Structure
Chemical Structure
Chemical Structure

Z-Leu-Leu-Leu-CHO [MG-132]

AG-CP3-0011
AdipoGen Life Sciences
CAS Number133407-82-6
Product group Chemicals
Estimated Purity>97%
Molecular Weight475.6
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Z-Leu-Leu-Leu-CHO [MG-132]
  • Delivery Days Customer
    10
  • CAS Number
    133407-82-6
  • Certification
    Research Use Only
  • Estimated Purity
    >97%
  • Molecular Formula
    C26H41N3O5
  • Molecular Weight
    475.6
  • Scientific Description
    Chemical. CAS: 133407-82-6. Formula: C26H41N3O5. MW: 475.6. Potent, cell permeable and selective, reversible proteasome inhibitor. Blocks degradation of short-lived proteins and induces a heat shock response. NF-kappaB activation inhibitor through IkappaB degradation. Cell permeable, reversible peptide aldehyde inhibitor. Calpain and cathepsin inhibitor. Has anticancer properties by inducing cell cycle arrest and activating apoptosis in various cancer cell lines. Has adjuvant/chemosensitizer potential. Neurite outgrowth stimulator in PC12 cells. Prevents beta-secretase cleavage. Autophagy activator. - Potent, cell permeable and selective, reversible proteasome inhibitor [2, 7]. Blocks degradation of short-lived proteins and induces a heat shock response [2, 6, 7]. NF-kappaB activation inhibitor through IkappaB degradation [3, 8]. Cell permeable, reversible peptide aldehyde inhibitor. Calpain and cathepsin inhibitor [4, 11]. Has anticancer properties by inducing cell cycle arrest and activating apoptosis in various cancer cell lines [8, 9, 12,13,15]. Has adjuvant/chemosensitizer potential [8]. Neurite outgrowth stimulator in PC12 cells [1]. Prevents beta-secretase cleavage [5, 10]. Autophagy activator [12, 14].
  • SMILES
    [H]C(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(CC(C)C)NC(=O)OCC1=CC=CC=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352209

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