(Z)-Orantinib

MedChem Express

(Z)-Orantinib [210644-62-5]

10

210644-62-5

Research Use Only

99.44

C18H18N2O3

310.35

(Z)-Orantinib ((Z)-SU6668) is a potent, selective, orally active and ATP competitive inhibitor of Flk-1/KDR , PDGFRbeta , and FGFR1 , with IC 50 s of 2.1, 0.008, and 1.2 microM, respectively. (Z)-Orantinib is a potent antiangiogenic and antitumor agent that induces regression of established tumors [1] [2] .

O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=CC=C3)=O)=C1C

-20°C,2°C to 8°C

12352200