(Z)-Orantinib

Biorbyt

(Z)-Orantinib

10

210644-62-5

Research Use Only

98.00%

C18H18N2O3

310.35

(Z)-Orantinib ((Z)-SU6668) is a potent, selective, orally active, and ATP-competitive inhibitor of Flk-1/KDR, PDGFRbeta, and FGFR1, with IC50 values of 2.1, 0.008, and 1.2 microM, respectively. (Z)-Orantinib is an effective antiangiogenic and antitumor agent that induces established tumor regression [1] [2].

C(=C\1/C=2C(NC1=O)=CC=CC2)\C3=C(C)C(CCC(O)=O)=C(C)N3

-20°C

12352200