Western blot analysis of extracts of various cell lines using ZBTB48 Polyclonal Antibody at 1:1000 dilution.
ZBTB48 Polyclonal Antibody
E-AB-61701
Product group Antibodies
Overview
- SupplierElabscience
- Product NameZBTB48 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionTelomere-binding protein that acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5-TTAGGG-3 repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres. Also acts as a transcription regulator that binds to promoter regions. Regulates expression of a small subset of genes, including MTFP1. Regulates expression the J and/or S elements in MHC II promoter. Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A.
- UNSPSC12352203