More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/ZC3H12A antibody [N3C3]

ZC3H12A antibody [N3C3]

GTX110807
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
DownloadDatasheet
Product group Antibodies
TargetZC3H12A
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    ZC3H12A antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID80149
  • Target name
    ZC3H12A
  • Target description
    zinc finger CCCH-type containing 12A
  • Target synonyms
    bifunctional endoribonuclease and deubiquitinase ZC3H12A; dJ423B22.1; endoribonuclease ZC3H12A; MCP-1 treatment-induced protein; MCP-induced protein 1; MCPIP; MCPIP1; MCPIP-1; monocyte chemotactic protein-induced protein 1; Reg1; regnase-1; ribonuclease ZC3H12A; zinc finger CCCH domain-containing protein 12A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ5D1E8
  • Protein Name
    Endoribonuclease ZC3H12A
  • Scientific Description
    ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.[supplied by OMIM]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • MCPIP1 regulates focal adhesion kinase and Rho GTPase-dependent migration in clear cell renal cell carcinoma. Gorka J et al., 2022 May 5, Eur J Pharmacol
    Read more
  • MCPIP1/Regnase-1 Expression in Keratinocytes of Patients with Hidradenitis Suppurativa: Preliminary Results. Krajewski PK et al., 2021 Jul 6, Int J Mol Sci
    Read more
  • Subversion of Lipopolysaccharide Signaling in Gingival Keratinocytes via MCPIP-1 Degradation as a Novel Pathogenic Strategy of Inflammophilic Pathobionts. Gasiorek A et al., 2021 Jun 29, mBio
    Read more
  • Extracellular mRNA transported to the nucleus exerts translation-independent function. Tomita T et al., 2021 Jun 16, Nat Commun
    Read more
  • MCPIP1-mediated NFIC alternative splicing inhibits proliferation of triple-negative breast cancer via cyclin D1-Rb-E2F1 axis. Chen F et al., 2021 Apr 6, Cell Death Dis
    Read more
  • Monocyte chemoattractant protein-induced protein 1 directly degrades viral miRNAs with a specific motif and inhibits KSHV infection. Kook I et al., 2021 May 7, Nucleic Acids Res
    Read more
  • MCPIP1 reduces HBV-RNA by targeting its epsilon structure. Li Y et al., 2020 Nov 27, Sci Rep
    Read more
  • The anti-inflammatory protein MCPIP1 inhibits the development of ccRCC by maintaining high levels of tumour suppressors. Gorka J et al., 2020 Dec 5, Eur J Pharmacol
    Read more
  • MCPIP1 inhibits Hepatitis B virus replication by destabilizing viral RNA and negatively regulates the virus-induced innate inflammatory responses. Li M et al., 2020 Feb, Antiviral Res
    Read more
  • Integrative genomics reveal a role for MCPIP1 in adipogenesis and adipocyte metabolism. Losko M et al., 2020 Dec, Cell Mol Life Sci
    Read more

Related products

Product group Antibodies
Biomatik
Zc3H12A Polyclonal AntibodyCAC10457
ApplicationsELISA, ImmunoHistoChemistry
TargetZC3H12A
  • SizePrice
Product group Antibodies
GeneTex
ZC3H12A antibodyGTX110808
ApplicationsWestern Blot
TargetZC3H12A
  • SizePrice
IHC-P analysis of human colon cancer tissue using GTX02811 ZC3H12A antibody. Dilution : 1:40
Product group Antibodies
GeneTex
ZC3H12A antibodyGTX02811
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetZC3H12A
  • SizePrice
Product group Antibodies
GeneTex
ZC3H12A antibody [HL1442]GTX636914
ApplicationsWestern Blot
TargetZC3H12A
  • SizePrice
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA037047(ZC3H12A Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)
Product group Antibodies
Cusabio
ZC3H12A AntibodyCSB-PA037047
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
TargetZC3H12A
  • SizePrice
Figure 1. Western blot analysis of MCPIP1/ZC3H12A using anti-MCPIP1/ZC3H12A antibody (A01688-2). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: human K562 whole cell lysates, Lane 2: human Raji whole cell lysates, Lane 3: human Sw620 whole cell lysates, Lane 4: human Hela whole cell lysates, Lane 4: rat spleen tissue lysates, Lane 5: rat kidney tissue lysates, Lane 6: mouse thymus tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-MCPIP1/ZC3H12A antigen affinity purified polyclonal antibody (Catalog # A01688-2) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for MCPIP1/ZC3H12A at approximately 73KD. The expected band size for MCPIP1/ZC3H12A is at 66KD.
Product group Antibodies
Boster Bio
Anti-MCPIP1/ZC3H12A Antibody Picoband(r)A01688-2-CARRIER-FREE
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetZC3H12A
  • SizePrice
Product group Antibodies
RayBiotech
Anti-ZC3H12A Antibody107-10940
TargetZC3H12A
  • SizePrice
Product group Antibodies
Bioss Antibodies
MCPIP1 Polyclonal Antibodybs-5792R
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetZC3H12A
  • SizePrice
Product group Antibodies
LifeSpan BioSciences
ZC3H12A / MCPIP1 AntibodyLS-C405140
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
TargetZC3H12A
  • SizePrice
Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
Product group Antibodies
Atlas Antibodies
Anti-ZC3H12A AntibodyHPA032052
ApplicationsImmunoHistoChemistry
TargetZC3H12A
  • SizePrice