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ProductsBack/ZEB1 antibody [N2C1], Internal

ZEB1 antibody [N2C1], Internal

Research Use Only
GTX105278
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetZEB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    ZEB1 antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6935
  • Target name
    ZEB1
  • Target description
    zinc finger E-box binding homeobox 1
  • Target synonyms
    AREB6; BZP; delta-crystallin enhancer binding factor 1; DELTAEF1; FECD6; negative regulator of IL2; NIL2A; posterior polymorphous corneal dystrophy 3; PPCD3; TCF8; transcription factor 8 (represses interleukin 2 expression); ZFHEP; ZFHX1A; zinc finger E-box-binding homeobox 1; zinc finger homeodomain enhancer-binding protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]).[supplied by OMIM]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • ZEB1 transcription factor promotes immune escape in melanoma. Plaschka M et al., 2022 Mar, J Immunother Cancer
    Read more
  • Tetrandrine Inhibits Epithelial-Mesenchymal Transition in IL-6-Induced HCT116 Human Colorectal Cancer Cells. Tsai SC et al., 2021, Onco Targets Ther
    Read more
  • E-cadherin Interacts With Posttranslationally-Modified AGO2 to Enhance miRISC Activity. Li JN et al., 2021, Front Cell Dev Biol
    Read more
  • Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages. Wang YY et al., 2020 Nov 26, Cancers (Basel)
    Read more
  • Curcumol Suppresses Triple-negative Breast Cancer Metastasis by Attenuating Anoikis Resistance via Inhibition of Skp2-mediated Transcriptional Addiction. Li CL et al., 2020 Oct, Anticancer Res
    Read more
  • PHRF1 promotes migration and invasion by modulating ZEB1 expression. Lee JY et al., 2020, PLoS One
    Read more
  • The Crosstalk between lncRNA-SNHG7/miRNA-181/cbx7 Modulates Malignant Character in Lung Adenocarcinoma. Pei YF et al., 2020 Jun, Am J Pathol
    Read more
  • A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and beta-catenin-ABCG2 signaling. Fang CH et al., 2020 Mar 13, J Biomed Sci
    Read more
  • Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer. Huang JY et al., 2019 Dec 20, Cancers (Basel)
    Read more
  • Breast Cancer Risk-Associated SNPs in the mTOR Promoter Form De Novo KLF5- and ZEB1-Binding Sites that Influence the Cellular Response to Paclitaxel. Chen Q et al., 2019 Nov, Mol Cancer Res
    Read more