ZEB1 antibody [N2C1], Internal
GTX105278
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetZEB1
Overview
- SupplierGeneTex
- Product NameZEB1 antibody [N2C1], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.13 mg/ml
- ConjugateUnconjugated
- Gene ID6935
- Target nameZEB1
- Target descriptionzinc finger E-box binding homeobox 1
- Target synonymsAREB6; BZP; delta-crystallin enhancer binding factor 1; DELTAEF1; FECD6; negative regulator of IL2; NIL2A; posterior polymorphous corneal dystrophy 3; PPCD3; TCF8; transcription factor 8 (represses interleukin 2 expression); ZFHEP; ZFHX1A; zinc finger E-box-binding homeobox 1; zinc finger homeodomain enhancer-binding protein
- HostRabbit
- IsotypeIgG
- Protein IDP37275
- Protein NameZinc finger E-box-binding homeobox 1
- Scientific DescriptionZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]).[supplied by OMIM]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- High expression of embryonic stem cell marker SSEA3 confers poor prognosis and promotes epithelial mesenchymal transition in hepatocellular carcinoma.Read more
- Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis.Read more
- Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-beta/TbetaRs signaling pathway.Read more
- FOXM1-CD44 Signaling Is Critical for the Acquisition of Regorafenib Resistance in Human Liver Cancer Cells.Read more
- ZEB1 transcription factor promotes immune escape in melanoma. Plaschka M et al., 2022 Mar, J Immunother CancerRead more
- Tetrandrine Inhibits Epithelial-Mesenchymal Transition in IL-6-Induced HCT116 Human Colorectal Cancer Cells. Tsai SC et al., 2021, Onco Targets TherRead more
- E-cadherin Interacts With Posttranslationally-Modified AGO2 to Enhance miRISC Activity. Li JN et al., 2021, Front Cell Dev BiolRead more
- Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages. Wang YY et al., 2020 Nov 26, Cancers (Basel)Read more
- Curcumol Suppresses Triple-negative Breast Cancer Metastasis by Attenuating Anoikis Resistance via Inhibition of Skp2-mediated Transcriptional Addiction. Li CL et al., 2020 Oct, Anticancer ResRead more
- PHRF1 promotes migration and invasion by modulating ZEB1 expression. Lee JY et al., 2020, PLoS OneRead more