ZNF395 Polyclonal Antibody

Reddot Biotech

ZNF395 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.8 mg/ml

Unconjugated

ZNF395

zinc finger protein 395

HD gene regulatory region-binding protein 2; HDBP2; HDBP-2; HD-regulating factor 2; HDRF-2; huntington disease gene regulatory region-binding protein 2; Huntington's disease gene regulatory region-binding protein 2; papillomavirus regulatory factor 1; papillomavirus regulatory factor PRF-1; papillomavirus-binding factor; PBF; PRF1; PRF-1; Si-1-8-14; zinc finger protein 395

Rabbit

IgG

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3,Aeo-CCGG-5,Aeo sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntingtons disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.

Human

-20°C

12352203