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ZWINT antibody

GTX107155
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetZWINT
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Overview

  • Supplier
    GeneTex
  • Product Name
    ZWINT antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID11130
  • Target name
    ZWINT
  • Target description
    ZW10 interacting kinetochore protein
  • Target synonyms
    HZwint-1, KNTC2AP, SIP30, ZWINT1, outer kinetochore KNL1 complex subunit ZWINT, SNAP25 interacting protein of 30 kDa, ZW10 interactor, kinetochore protein, human ZW10 interacting protein-1, zwint-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO95229
  • Protein Name
    Outer kinetochore KNL1 complex subunit ZWINT
  • Scientific Description
    This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Kim JH, Youn Y, Lee JC, et al. Involvement of the NF-κB signaling pathway in proliferation and invasion inhibited by Zwint-1 deficiency in Pancreatic Cancer Cells. J Cancer. 2020,11(19):5601-5611. doi: 10.7150/jca.46173
    Read this paper
  • Zhou H, Wang T, Zheng T, et al. Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Nat Commun. 2016,7:10151. doi: 10.1038/ncomms10151
    Read this paper
  • Wei R, Ngo B, Wu G, et al. Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint. Mol Biol Cell. 2011,22(19):3584-94. doi: 10.1091/mbc.E11-01-0012
    Read this paper