ZWINT antibody
GTX107155
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetZWINT
Overview
- SupplierGeneTex
- Product NameZWINT antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID11130
- Target nameZWINT
- Target descriptionZW10 interacting kinetochore protein
- Target synonymshuman ZW10 interacting protein-1; HZwint-1; KNTC2AP; SIP30; SNAP25 interacting protein of 30 kDa; ZW10 interactor; ZW10 interactor, kinetochore protein; ZWINT1; zwint-1
- HostRabbit
- IsotypeIgG
- Protein IDO95229
- Protein NameZW10 interactor
- Scientific DescriptionThis gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Involvement of the NF-kappaB signaling pathway in proliferation and invasion inhibited by Zwint-1 deficiency in Pancreatic Cancer Cells. Kim JH et al., 2020, J CancerRead more
- Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Zhou H et al., 2016 Jan 8, Nat CommunRead more
- Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint. Wei R et al., 2011 Oct, Mol Biol CellRead more