
WB analysis of peripheral blood mononucleocytes lysate using GTX88237 Zyxin antibody, Internal. Dilution : 0.1microg/ml Loading : 35microg protein in RIPA buffer
Zyxin antibody, Internal
GTX88237
Overview
- SupplierGeneTex
- Product NameZyxin antibody, Internal
- Delivery Days Customer7
- Application Supplier NoteWB: 0.1-0.3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID7791
- Target nameZYX
- Target descriptionzyxin
- Target synonymsESP-2; HED-2; zyxin; zyxin-2
- HostGoat
- IsotypeIgG
- Protein IDQ15942
- Protein NameZyxin
- Scientific DescriptionFocal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203