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(+/-)12-HEPE

ORB1985142
Biorbyt
CAS Number81187-21-5
Product group Chemicals
Estimated Purity98.00%
Molecular Weight318.457
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Overview

  • Supplier
    Biorbyt
  • Product Name
    (+/-)12-HEPE
  • Delivery Days Customer
    10
  • CAS Number
    81187-21-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.00%
  • Molecular Formula
    C20H30O3
  • Molecular Weight
    318.457
  • Scientific Description
    (+/-)12-HEPE is produced by non-enzymatic oxidation of EPA, resulting in equal amounts of 12(S)-HEPE and 12(R)-HEPE. The biological activity of (+/-)12-HEPE is likely mediated by one of the individual isomers, primarily the 12(S) isomer in mammalian systems. 12-HEPE inhibits platelet aggregation with an IC50 of 24 microM, similar to 12-HETE (IC50 = 25 microM), and both compounds also inhibit U46619-induced contraction of rat aorta with IC50 values between 8.6-8.8 microM. [1][2]
  • SMILES
    CC\C=C/C\C=C/CC(O)\C=C\C=C/C\C=C/CCCC(O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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