(+/-)12-HEPE [81187-21-5]
T35506
CAS Number81187-21-5
Product group Chemicals
Molecular Weight318.457
Overview
- SupplierTargetMol Chemicals
- Product Name(+/-)12-HEPE [81187-21-5]
- Delivery Days Customer44
- CAS Number81187-21-5
- CertificationResearch Use Only
- Chemical Name(±)12-HEPE
- Molecular FormulaC20H30O3
- Molecular Weight318.457
- Scientific Description(+/-)12-HEPE is produced by non-enzymatic oxidation of EPA, resulting in equal amounts of 12(S)-HEPE and 12(R)-HEPE. The biological activity of (+/-)12-HEPE is likely mediated by one of the individual isomers, primarily the 12(S) isomer in mammalian systems. 12-HEPE inhibits platelet aggregation with an IC50 of 24 microM, similar to 12-HETE (IC50 = 25 microM), and both compounds also inhibit U46619-induced contraction of rat aorta with IC50 values between 8.6-8.8 microM. [1][2]
- Shelf life instruction3 years
- SMILESCC\C=C/C\C=C/CC(O)\C=C\C=C/C\C=C/CCCC(O)=O
- Storage Instruction-20°C
- UNSPSC12352200
MSDS
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